Quirem Medical is an emerging medical device company with a mission to develop the next generation microspheres for targeted interventional treatment of liver malignancies. It is based in Deventer, the Netherlands and is a spin-off company from the University Medical Center in Utrecht. QuiremSpheres®, the next generation of radio-embolization microspheres, are the only commercially available microspheres that contain the radioactive isotope Holmium-166. In recent trials, holmium microspheres were shown to be safe and effective for the treatment of advanced liver cancer. Unlike the widely adopted Yttrium-90 microspheres, QuiremSpheres® can be visualized in low concentrations by means of SPECT and MRI. This allows clinicians to quantitatively assess the distribution of microspheres in the liver, enabling accurate evaluation of treatment directly after the radio-embolization procedure.